Analysis of the Diluents Used for Rubella Virus Hemagglutination and Hemagglutination-Inhibition Tests1

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Analysis of the diluents used for rubella virus hemagglutination and hemagglutination-inhibition tests.

A new diluent (ADGP) for the rubella virus hemagglutination (HA) and hemagglutination-inhibition (HI) tests is described. It was found that the HA and HI titers and the erythrocyte agglutination pattern were improved in ADGP compared to previously described diluents. The influence of the components of ADGP and of various test conditions on optimal HA and HI results were examined.

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An improved diluent for rubella hemagglutination and hemagglutination-inhibition tests.

Rubella hemagglutinating (HA) antigen was prepared in BHK-21 tissue as 5% cell suspensions and from unconcentrated and 20x concentrated infected supernatant fluids. In some instances, unconcentrated fluids were treated with Tween 80 and ether; cell suspensions were treated with ether alone. Preparations were tested for HA activity in dextrose-gelatin-Veronal (DGV) buffer solutions; 0.85% NaCl; ...

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Comparison of hemagglutination inhibition test and enzyme-linked immunosorbent assay for determining antibody to rubella virus.

The hemagglutination inhibition test (HAI) and the enzyme-linked immunosorbent assay (ELISA) for detecting antibody to rubella virus were compared by testing 25 sets of paired sera taken before and after infection and 10 sets of sera taken during acute and convalescent stages of the disease and by screening 700 serum samples from the Collaborative Perinatal Project, NIH/NINCDS. The tests were f...

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Specificity of the passive hemagglutination test for antibody to rubella virus and the passive hemagglutination response after vaccination.

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Hemagglutination - Inhibition Assay For

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ژورنال

عنوان ژورنال: Applied Microbiology

سال: 1969

ISSN: 0003-6919

DOI: 10.1128/aem.18.2.221-227.1969